PITTSFORD, N. Air Max Italia Scarpe .Y. -- Rex Ryans new-look defense is running out of rookie starters.The Bills two top draft picks are now sidelined with injuries.The team announced Wednesday that linebacker Reggie Ragland will have surgery to repair a torn ligament in his left knee. Ryan said he expects Ragland to miss the entire season.Ragland was Buffalos second-round pick out of Alabama. The Bills are already down their first-round pick, linebacker Shaq Lawson, who is expected to miss at least the first month of the season recovering from shoulder surgery in May.Well, we were excited about those two guys. Obviously, we think theyre rare talents and thats not going to change either based on an injury, Ryan said following practice. Its just unfortunate that weve got to be a little more patient than maybe we wanted to.Ragland was hurt during practice Friday. He was going after a ball carrier on a run play when he pulled up suddenly and went to the ground without being hit.Initial tests were inconclusive because of swelling around the knee. The severity of the injury was revealed after a follow-up test.The Bills thought so highly of Ragland that they considered selecting him with their first pick, 19th overall. They instead chose Lawson, a highly touted pass rusher out Clemson whose stock dropped because of concerns he might need shoulder surgery to repair an injury that nagged him in college.In the second round, the Bills traded up eight spots to select Ragland with the 41st pick.Both were immediately pegged as starters on a defense being overhauled after it underperformed during Ryans first season last year.Ragland spent the entire offseason playing one of two middle linebacker spots, alongside returning starter Preston Brown.Veteran free agent addition Zach Brown will replace Ragland. The Bills also restocked the position by signing veteran free agents Brandon Spikes and David Hawthorne on Sunday.Lawson was supposed to immediately step in to fill the outside position left open after the Bills cut Mario Williams in March. Lawsons backup, veteran Manny Lawson, is also hurt. Hes expected to miss most of the preseason with a partially torn pectoral muscle.Despite the injuries, Ryan is sticking with the offseason vow he made in saying Buffalos defense will be better from last year, when it ranked 20th in yards allowed and managed 21 sacks -- a franchise-low for a 16-game season.Ive said all along our defense will be much improved, and Ill stand by that, Ryan said. Its really unfortunate for the young man and for our team because we know hes a fine player. But guys will step up.Game notes WR Greg Salas left practice with a hamstring injury. ... CB Sterling Moore left practice with a head injury and is being monitored for a concussion. ... The Bills practice Thursday night before opening their preseason hosting Indianapolis on Saturday.---AP NFL website: www.pro32.ap.org and www.twitter.com/AP-NFL Air Max Ingrosso . The Cleveland Indians, Tampa Bay Rays, and Texas Rangers all won on Sunday meaning the Rangers will host the Rays in a play-in game on Monday. Air Max 1 Scontate . Inter president Erick Thohir says in a club statement on Wednesday that Vidic is "one of the worlds best defenders and his qualities, international pedigree, and charisma will be an asset. http://www.airmaxitaliascarpe.it/ . -- Damian Lillard and LaMarcus Alrdridge were again the go-to duo for the Trail Blazers against the Kings. SYRACUSE, N.Y. -- Andrew White says its way too early to call himself an X factor for No. 18 Syracuse. The fifth-year transfer from Nebraska may just be the difference maker, however, for a team that looks like it may be one of the nations elite.White, who shot 41 percent from 3-point range a year ago, signed with the Orange the day before fall classes started. He gives the Orange a dimension they appeared to be lacking entering the season.I definitely think hes a difference maker, said fellow fifth-year transfer John Gillon. The way he spreads the floor and how quick his release is theres really not five people who can shoot like that in the nation.White scored 19 points, Tyler Lydon had 17, and Syracuse went on a 14-0 run in the first half to take control and overpower Holy Cross 90-46 on Tuesday night.Syracuse (2-0) shot 58 percent from the field and was 13 for 25 on 3-pointers. White went 5 of 10 from beyond the arc after going 2 of 7 in the Oranges season opener against Colgate.Hes a huge piece of this team, Lydon said. He can do a lot of great things on the court. Adding him was huge for us. Anytime you have a guy who can space the floor like thats huge.White, a modest sort, preferred to let his teammates do the talking.Id rather that question be answered by my teammates, White said. Theyre the ones evaluating what my value is. I just try to come in and take care of business, take pressure off my teammates. I think thats what Ill do most.And just two games into the season, White says talk of his importance is a tad premature.I think were all critical. I think were all X factors. As far as me being the X factor I think its a little early now to be saying that. Im just trying to come in and do my job.And his job is knocking down 3s, a skill in which he has supreme confidence.My motto is if a shoot a shot its supposed to go in, he added. Thats why I dont get too excited when I hit a three or celebrate too much. My coaches and teammates expect the shot to go in when I attempt it.Coach Jim Boeheim praised White.He was geared up tonight. He was ready to go. He was focused in, Boeheim said. Hees a shooter. Scarpe Air Max 96 Scontate. Obviously thats what he does. Were happy we have him here.Tyus Battle was 3 of 5 from long range, while Gillon made two while adding 15 points, nine assists and just one turnover off the bench.Anthony Thompson had 12 points, while Robert Champion and Malachi Alexander had eight apiece for the Crusaders (0-2). The Crusaders shot just 31 percent for the game.Asked what he would take away from the game, Holy Cross coach Bill Carmody had a succinct response: Nothing.Besides their 3-point attack, the Orange tallied 18 second-chance points, had 32 inside the paint, and scored 31 points off Holy Cross turnovers. The Orange outrebounded the smaller Crusaders 39-27. At one point in the first half, Syracuse had a 16-3 advantage on the boards.The Orange led 22-14 when they went on their 14-0 blitz to take control. The run featured four 3-pointers, two by White and one each by Frank Howard and Battle. Syracuse led 49-23 at the half.BIG PICTURE:Holy Cross: Its not fair to judge Holy Crosss outlook for the 2016-17 season based on Tuesdays outcome, but we may know more after Fridays matchup against UMass.Syracuse: This is one of Jim Boeheims best offensive teams in years. The Orange can beat teams inside and out.POLL IMPLICATIONS: With the nations top teams playing each other this week, the Orange could find themselves moving up in the rankings.SOPHOMORE SLUMP OVER: Tyler Lydon was 0-for-8 from beyond the arc in Syracuses two exhibition games and 0-for-3 in the season opener but he was 2-of-3 Tuesday.MICROWAVE: Gilllon is proving to be quite the spark off the bench for Boeheim. The transfer from Colorado State now has 28 points, 15 assists and just one turnover in two games.NO TREY, NO WAY: Holy Cross was just of 9-of-32 from 3 for 28 percent.UP NEXT:Holy Cross tries for its first win of the young season when the Crusaders host UMass on Sunday.Syracuse, a bubble team that made last years NCAA Tournament, hosts Monmouth, a bubble team that did not, Friday. ' ' '